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Robert R Luedtke Selected Research

Dopamine Receptors (Dopamine Receptor)

5/2021Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands.
1/2019Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands.
1/2015Bitropic D3 Dopamine Receptor Selective Compounds as Potential Antipsychotics.
1/2013The effect of SV 293, a D2 dopamine receptor-selective antagonist, on D2 receptor-mediated GIRK channel activation and adenylyl cyclase inhibition.
6/2011Synthesis and characterization of selective dopamine D₂ receptor ligands using aripiprazole as the lead compound.
3/2011Synthesis and pharmacological evaluation of fluorine-containing D₃ dopamine receptor ligands.
2/2011Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on L-dopa dependent animal involuntary movements in rats.
1/2011Decreased striatal dopamine receptor binding in primary focal dystonia: a D2 or D3 defect?
11/2010Subtype selectivity of dopamine receptor ligands: insights from structure and ligand-based methods.
5/2009Evaluation of D2 and D3 dopamine receptor selective compounds on L-dopa-dependent abnormal involuntary movements in rats.
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Robert R Luedtke Research Topics

Disease

7Substance-Related Disorders (Drug Abuse)
01/2019 - 08/2007
5Parkinson Disease (Parkinson's Disease)
05/2021 - 05/2009
4Dyskinesias (Dyskinesia)
05/2021 - 05/2009
3Schizophrenia (Dementia Praecox)
01/2015 - 08/2009
3Cocaine-Related Disorders (Cocaine Addiction)
12/2013 - 02/2005
2Nervous System Diseases (Neurological Disorders)
03/2011 - 11/2010
1Traumatic Brain Injuries (Traumatic Brain Injury)
05/2015
1Alzheimer Disease (Alzheimer's Disease)
05/2015
1Stroke (Strokes)
05/2015
1Gynecomastia
01/2015
1Diabetes Mellitus
01/2015
1Hyperglycemia
01/2015
1Dyslipidemias (Dyslipidemia)
01/2015
1Weight Gain
01/2015
1Movement Disorders (Movement Disorder)
01/2013
1Bipolar Disorder (Manic Depressive Psychosis)
06/2011
1Dystonia (Limb Dystonia)
01/2011
1Dystonic Disorders (Writer's Cramp)
01/2011
1Neuroblastoma
09/2004

Drug/Important Bio-Agent (IBA)

12Dopamine Receptors (Dopamine Receptor)IBA
05/2021 - 09/2004
6Dopamine D3 ReceptorsIBA
12/2018 - 08/2007
5LigandsIBA
05/2021 - 08/2007
4Levodopa (L Dopa)FDA LinkGeneric
05/2021 - 05/2009
3N- (4- (4- (2,3- dichlorophenyl)piperazin- 1- yl)but- 2- enyl)- 4- pyridine- 2- ylbenzamideIBA
02/2011 - 08/2007
2Oxidopamine (6 Hydroxydopamine)IBA
05/2021 - 05/2009
2Antipsychotic Agents (Antipsychotics)IBA
01/2015 - 06/2011
2Dopamine Agonists (Dopamine Agonist)IBA
08/2009 - 05/2009
2Dopamine (Intropin)FDA LinkGeneric
08/2009 - 09/2004
2SK&F 81297IBA
05/2009 - 05/2009
1Cholinergic Agents (Cholinergics)IBA
05/2015
1Cocaine (Cocaine HCl)IBA
12/2013
11- ((5- methoxy- 1H- indol- 3- yl)methyl)- 4- (4- (methylthio)phenyl)piperidin- 4- olIBA
01/2013
1Antidepressive Agents (Antidepressants)IBA
06/2011
1Aripiprazole (Abilify)FDA Link
06/2011
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
02/2011
1N- (4- (4- (2,3- dichlorophenyl)piperazin- 1- yl)butyl)- 4- (pyridin- 3- yl)benzamideIBA
02/2011
1SpiperoneIBA
01/2011
1phenylpiperazineIBA
05/2009
1Bromocriptine (Parlodel)FDA LinkGeneric
05/2009
1pyridineIBA
08/2007
1Pharmaceutical PreparationsIBA
02/2005
1Phosphotransferases (Kinase)IBA
09/2004

Therapy/Procedure

2Therapeutics
01/2019 - 08/2014
1Self Administration (Administration, Self)
12/2013